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Body Weight May Affect Survival After Colon and Rectal Cancer

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Body mass index and colorectal cancer recurrence and mortality A nationwide cohort study in Denmark.DOI 10.1002ijc.70248

Maintaining a healthy body weight is important for overall health. A new nationwide study from Denmark suggests that body weight may also influence survival after colorectal cancer treatment.Researchers studied thousands of patients who had surgery to remove stage I–III colon or rectal cancer. They followed these patients for several years to see whether body mass index (BMI) affected cancer recurrence or survival.
The results showed that body weight did not affect whether the cancer came back. However, weight did influence survival. Patients who were underweight or severely obese had a higher risk of dying after treatment.
The effect was particularly noticeable in people with rectal cancer, especially younger men with severe obesity. Other factors like smoking, alcohol use, and existing health conditions also influenced survival outcomes.Interestingly, people with moderate overweight did not show worse outcomes compared with those at normal weight. This suggests that extreme body weight—either too low or too high—may pose the greatest risk.

The study highlights the importance of good nutrition and healthy weight management during and after cancer treatment. Doctors may use this information to identify patients who need extra support to improve long-term outcomes.

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Dr Harsh Shah - GI & HPB Oncosurgeon in Ahmeadbad
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