AI-Assisted Transcriptomic Signatures for Personalizing Chemotherapy in Pancreatic Ductal Adenocarcinoma (PDAC)
AI-Assisted Transcriptomic Signatures for Personalizing Chemotherapy in Pancreatic Ductal Adenocarcinoma (PDAC)
Maulana Azad Medical College, Delhi, GB Pant Hospital, Delhi
Holds the highest degrees in Oncology - DrNB, MCh
Having 15+ years of experience in treating
11750+ Patients have been successfully
treated
15+ years of work experience as a pancreatic cancer specialist
22+ Awards received by Dr. Shah for his achievements
In the meticulous management of pancreatic cancer, Dr. Harsh Shah employs advanced techniques that set the standard for care. At the best hospital for pancreatic cancer in India, under Dr. Shah’s guidance, cutting-edge techniques are utilized for proper diagnosis and early treatment. Patients benefit from his commitment to staying abreast of the latest advancements, ensuring that the treatment offered is at the forefront of medical innovation. As the best pancreatic surgeon in India, Dr. Shah’s techniques reflect a dedication to providing the highest quality care.
Exocrine Pancreatic Cancer:
⦿ Description: This is the most common type, making up approximately 95% of all pancreatic cancer cases.
⦿ Location: It develops in the exocrine cells of the pancreas, which produce enzymes for digestion.
⦿ Common Form: The most prevalent form is pancreatic adenocarcinoma.
Endocrine Pancreatic Cancer:
⦿ Alternative Names: Also known as neuroendocrine tumors or islet cell tumors.
⦿ Origin: This type of pancreatic cancer starts in the endocrine cells of the pancreas.
⦿ Function: Endocrine cells produce hormones that regulate various bodily functions.
⦿ Prevalence: Relatively rare, comprising about 5% of pancreatic cancer cases.
⦿ Abdominal Pain
⦿ Jaundice (Yellowing of the Skin and Eyes)
⦿ Unexplained Weight Loss
⦿ Loss of Appetite
⦿ Nausea
⦿ Fatigue
⦿ Changes in Bowel Movements
⦿ Genetic mutations: Inherited or acquired mutations play a key role.
⦿ Age and gender: Risk increases with age; slightly higher in men.
⦿ Smoking: Major lifestyle factor linked to pancreatic cancer.
⦿ Chronic pancreatitis: Long-term inflammation elevates risk.
⦿ Diabetes: People with long-standing diabetes face higher susceptibility.
⦿ Family history: Increased risk if close relatives had pancreatic cancer.
⦿ Obesity: Obesity and excess body weight contribute to higher risk.
⦿ Dietary factors: High intake of red meat and processed meats may play a role.
Pancreatic cancer is staged based on the extent of the disease. The stages of pancreatic cancer are as follows:
Stage 0: Also known as carcinoma in situ, cancer is confined to the top layers of cells in the pancreas and has not spread deeper.
Stage I: Cancer is localized to the pancreas and has not spread to nearby lymph nodes or distant sites.
Stage II: Cancer has spread to nearby lymph nodes but not to distant sites.
Stage III: Cancer has spread to major blood vessels near the pancreas or to nearby lymph nodes.
Stage IV: Cancer has spread to distant organs, such as the liver, lungs, or distant lymph nodes.
CT Scan: A CT scan, short for computed tomography scan, is a medical imaging technique that uses X-rays and computer processing to create detailed cross-sectional images of the body.
Dr. Harsh and his staff are amazing. I’m so glad I found them for my friend having pancreas cancer. he listened to me, I mean actually listened to me and heard me. He managed everything with perfection. We are happy and feel that one should come here if looking for best gastrointestinal & pancreatic cancer surgeon in Gujarat.
According to me, Dr. Harsh Shah is the best pancreatic cancer specialist in Ahmedabad. He has operated on my mother who was suffering from neuroendocrine tumor of pancreas. An operation called distal pancreatectomy of the pancreas was performed. Now my mother is fine and we are being discharged today. I would say we have been given the best treatment for pancreatic cancer. Thanks to all the hospital staff. I would highly recommend Dr. Harsh Shah for any pancreatic cancer treatment.
Dr. Harsh and his staff are amazing. I’m so glad I found them for my friend having pancreas cancer. he listened to me, I mean actually listened to me and heard me. He managed everything with perfection. We are happy and feel that one should come here if looking for best gastrointestinal & pancreatic cancer surgeon in Gujarat.
According to me, Dr. Harsh Shah is the best pancreatic cancer specialist in Ahmedabad. He has operated on my mother who was suffering from neuroendocrine tumor of pancreas. An operation called distal pancreatectomy of the pancreas was performed. Now my mother is fine and we are being discharged today. I would say we have been given the best treatment for pancreatic cancer. Thanks to all the hospital staff. I would highly recommend Dr. Harsh Shah for any pancreatic cancer treatment.
Explore surgical photographs with caution. Please be advised that viewer discretion is recommended.
Assisted by robotic systems to enhance precision in surgical procedures.
Less invasive procedures designed for quicker recovery.
Utilizes the immune system to combat pancreatic cancer.
Targets specific features of cancer cells for precise treatment.
Delivers focused radiation to the tumor, sparing healthy tissues.
⦿ Distal Pancreatosplenectomy is a surgery that removes the left part of the pancreas and the spleen. It is usually done when pancreatic cancer is found in the body or tail of the pancreas. The goal of the procedure is to take out the tumor and any nearby affected tissue.
⦿ This surgery can be done using minimally invasive methods like laparoscopy or robotic-assisted surgery.
⦿ After the procedure, patients might need additional treatments such as chemotherapy or radiation therapy.
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Pancreatic cancer is diagnosed by a team of healthcare professionals, including Gastroenterologists, Radiologists and Pathologists. They analyze the patient’s symptoms, medical history, and perform various tests.
Pancreatic cancer is most curable when diagnosed at an early stage (typically stages 0 or I), before it has spread beyond the pancreas. However, even in later stages, treatment options are available to manage symptoms and extend survival.
Stage 4 pancreatic cancer is the most advanced stage, indicating that the cancer has spread to distant organs or tissues beyond the pancreas. Treatment at this stage focuses on palliative care to alleviate symptoms and improve the patient’s quality of life.
The first test to evaluate suspected pancreatic cancer is typically an imaging test, such as a computed tomography (CT) scan or an endoscopic ultrasound (EUS), which helps visualize the pancreas and detect any abnormalities.
The best scan to detect cancer depends on the type and location of the cancer. Different scans, such as CT scans, MRI scans, PET scans, and ultrasound, have their strengths and limitations. The choice is determined by the specific needs of the patient and the suspected type of cancer.
Both MRI (magnetic resonance imaging) and CT (computed tomography) scans are valuable for detecting and diagnosing cancer. The choice depends on factors like the type of cancer, location, and specific clinical requirements. In some cases, a combination of both scans may be used for a comprehensive evaluation.
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