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Dr Harsh Shah - GI & HPB OncoSurgeon
Dr Harsh Shah - GI & HPB OncoSurgeon

A New Way to Detect Acid Reflux Damage More Accurately

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Lower mean nocturnal baseline impedance in erosive reflux disease. DOI 10.1093dotedoaf129

Acid reflux, or GERD, can cause burning in the chest, sore throat, and even long-term damage to the food pipe. But sometimes, tests don’t clearly show if someone has the disease—especially when the endoscopy looks normal.Doctors are now studying a new way to check for damage called “MNBI” (mean nocturnal baseline impedance). It sounds technical, but it simply measures how well the lining of your food pipe is working during the night. Lower numbers mean more damage.

This study looked at 550 people with reflux symptoms. It found that people with more serious forms of reflux—like those with visible damage or Barrett’s esophagus—had lower MNBI numbers. People with a higher body weight also had lower scores, suggesting more irritation in the food pipe lining.

Interestingly, people who were already taking acid-suppressing medicines had slightly higher MNBI readings. This means the medicine might make the damage harder to spot on this test, so doctors may ask patients to stop medication before testing.

This new test may help catch reflux damage earlier, even when other tests don’t give clear answers. If you have long-lasting reflux symptoms, it’s worth asking your doctor about the latest testing options to better understand what’s happening inside your body.

DOI: 10.1093/dote/doaf129

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Dr Harsh Shah - GI & HPB Oncosurgeon in Ahmeadbad
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