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Major Cancer Surgery Can Benefit Selected Patients Over 75

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Survival and morbidity in elderly patients treated with cytoreductive surgery and HIPEC for colorectal peritoneal metastases a population-based study.DOI 10.108002656736.2026.2620731

When colorectal cancer spreads to the lining of the abdomen, doctors may treat it with an intensive procedure called cytoreductive surgery with HIPEC. This surgery removes visible tumors and then delivers heated chemotherapy directly into the abdomen to kill remaining cancer cells.
Because the operation is complex, doctors sometimes hesitate to offer it to older patients. A new study from Sweden looked at whether patients aged 75 or older had worse outcomes than younger patients.
Researchers analyzed 592 patients treated with this procedure. Most were younger than 75, but 39 patients were 75 or older.
The results were encouraging. Survival rates were similar in both age groups, meaning older patients benefited just as much from the treatment as younger patients. Serious complications after surgery were also comparable, and no patients aged 75 or older died during their hospital stay.
Instead of age, other factors had a bigger effect on survival. Patients did worse when cancer had spread widely in the abdomen or when surgeons could not remove all visible tumors.
These findings suggest that age alone should not prevent someone from receiving CRS-HIPEC surgery. With careful patient selection and experienced surgical teams, older adults can safely undergo this treatment and achieve meaningful outcomes.

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Dr Harsh Shah - GI & HPB Oncosurgeon in Ahmeadbad
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