The Prognostic Significance of Tumor Deposits in Gastric Cancer

A comprehensive multicenter study involving 781 patients with locally advanced gastric cancer (LAGC) revealed significant findings about tumor deposits (TDs). The study highlighted that TDs are associated with larger tumor size (≥ 5 cm) and vascular invasion. Independent risk factors for poor prognosis include TD positivity, tumor diameter, advanced pT4a stage, and vascular invasion. Particularly, patients with TDs at pT4a and pN3b stages exhibit notably lower 5-year overall and disease-free survival rates. These insights underscore the necessity of considering TDs in the prognosis and tailored management of LAGC. For further details, refer to the full study here: https://doi.org/10.1245/s10434-024-15508-1